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The Journal of Nuclear Medicine Vol. 16 No. 11 1076-1079
© 1975 by Society of Nuclear Medicine
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Calculation of an Estimate of Thyroxine-Binding Globulin Capacity

Martin L. Nusynowitz and Anthony R. Benedetto

William Beaumont Army Medical Center, El Paso, Texas

Correspondence: For reprints contact: Col. M. L. Nusynowitz, P.O. Box 70014, William Beaumont Army Medical Center, El Paso, Texas 79920.

ABSTRACT

An estimate of the serum thyroxine-binding globulin (TBG) may be computed from determinations of serum thyroxine and triiodothyronine uptake. A general equation for this computation is presented and a computer program for the calculation of the estimating parameters is discussed. With these methods, the regression equation for the calculated TBG and the observed TBG is the line of identity, and the correlation coefficients from determinations on data from two laboratories were +0.88 and +0.96. The calculated TBG may be used as a screening test for abnormalities of thyroxine binding protein and as an aid in the proper interpretation of thyroid function studies.







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Copyright © 1975 by the Society of Nuclear Medicine.