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Cerebral Ventricle Visualization During Brain Scanning with ^99mTc-Pertechnetate

Ohio State University, Columbus, Ohio

Correspondence: For reprints contact: Lawrence R. Fulmer, Div. of Nuclear Medicine, Dept. of Radiology, Ohio State University Hospitals, 410 West 10th Ave., Columbus, Ohio 43210.

ABSTRACT

Ventricular visualization during ^99mTc-pertechnetate brain scanning is probably due to increased permeability of the blood spinal fluid barrier to the technetium ion. It has been shown by others that various disease states affect the permeability of the blood spinal fluid barrier in adults and these permeability changes may be even more striking in infancy. The ventricular visualization noted in four patients was due to intraventricular infection in three (proven in two, suspected in one) and secondary to hyperthermic or anoxic damage to the CNS in one. The presence or absence of ventricular visualizalion seems to bear a direct relationship to the severity of the intraventricular infection (as determined by CSF analysis).

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