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Resolution of Increased Splenic Size and Uptake of ^99mTc-Sulfur Colloid Following Removal of a Malignant Melanoma

USAF Medical Center, Scott AFB, Illinois

Correspondence: For reprints contact: William C. Klingensmith III, Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, 615 N. Wolfe St., Baltimore, Md. 21205.

ABSTRACT

Increased splenic uptake of ^99mTc-sulfur colloid (TcSC) in patients with malignant melanoma and no evidence of liver disease has recently been reported. In a similar patient serial liver—spleen studies demonstrated the resolution of splenomegaly and increased splenic uptake of TcSC following the surgical removal of a malignant melanoma of the eye.