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Scintigraphic Detection of Deep-Vein Thrombosis with ¹³¹I-Fibrinogen

Temple University Medical School and Hospital, Philadelphia, Pennsylvania

Correspondence: For reprints contact: N. David Charkes, Dept. of Nuclear Medicine, Temple University Hospital, 3401 N. Broad St., Philadelphia, Pa. 19140.

ABSTRACT

Twenty-nine postoperative patients and 8 with fractured hip were injected with ¹³¹I-fibrinogen and whole-body scintiscans made at frequent intervals for a week. Venography was performed in 20 of the patients and the concordance between the two studies was 93%. Deep-vein thrombi were found in eight postoperative patients (28%) and in three with fractured hip (38%). Scintiscanning with ¹³¹I-fibrinogen has certain advantages over the ¹²⁵I-fibrinogen method including the possibility of detecting iliac-vein thrombi.