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Scintigraphic Study of Pulmonary Blood Flow Distribution in Cystic Fibrosis

Hopital Saint-Pierre, Brussels University, Brussels, Belgium

Correspondence: For reprints contact: A. Piepsz, Dept. Pediatrics, Hopital Saint-Pierre, 322 rue Haute, 1000, Brussels, Belgium.

ABSTRACT

Considerable alterations of lung perfusion are evident in cystic fibrosis although no primary vascular involvement has been shown. Seventy-three children from the age of 6 weeks to 19 years have been investigated by means of perfusion scintigraphy with a scintillation camera. Special attention was paid to the actual clinical status (remission or acute phase) at the time of examination. In the remission phase, correlation was found between the perfusion abnormalities and the severity of the disease. In the acute phase, striking transient alterations develop; their prognostic value should be determined by further investigation.