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Hyperbaric Cisternography: Studies in an Inanimate Model and Monkeys

University of California, School of Medicine, La Jolla, California

Correspondence: For reprints contact: Samuel E. Halpern, Div. of Nuclear Medicine. University Hospital of San Diego County, 225 W. Dickinson St., San Diego, Calif. 92103.

ABSTRACT

A study was made concerning the addition of hyperbaric dextrose solutions to a radiopharmaceutical and the Trendelenburg position in an effort to improve the technical quality of cisternography. Studies were performed in a mock spinal canal and in Macaca nemestrina monkeys. The rate of tracer movement was enhanced in the inanimate model. The disappearance time of the radiopharmaceutical over the lumbar area in the monkeys was markedly shortened. Greater quantities of tracer material appeared at the basal cisterns with the use of the hyberbaric system than when nonhyperbaric solutions were used. No evidence of artifact formation was found. This study suggests that the technique may be of utility in cisternography involving humans.