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Quantitative Section Scanning Using Orthogonal Tangent Correction

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Correspondence: For reprints contact: David E. Kuhl, Div. of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, Pa. 19104.

ABSTRACT

Orthogonal tangent correction (OTC) is introduced as an improvement of the processing technique for transverse section imaging. The initial step in this processing technique is to take an orthogonal pair of tangent data lines and form a matrix distribution that reflects the proportionality that exists between them. The matrix data are then redistributed to conform to the proportionality of each succeeding orthogonal pair of tangent lines without destroying the compatibility achieved in previous steps. The final section matrix is a high contrast image of the cross-section, the matrix distribution is compatible with all tangent values, and there is a linear relationship between matrix counts and radioactivity in the scanned object. We have already applied Orthogonal Tangent Correction to clinical brain scanning with advantage but we regard its more important role to be as another significant step toward quantitative imaging for estimate of radioactivity localised in three dimensions.

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