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Measurement of Left Ventricular Ejection Fraction

The Edward Mallinckrodt Institute of Radiology and the Biomedical Computer Laboratory, Washington University School of Medicine, St. Louis, Missouri

Correspondence: For reprints contact: Roger H. Secker-Walker, Div. of Nuclear Medicine, Firmin Desloge Hospital, 1325 S. Grand Ave., St. Louis, Mo. 63104.

ABSTRACT

Left ventricular ejection fraction has been determined in 16 patients using ^99mTc-human serum albumin and a gamma scintillation camera and an electrocardiogram interfaced to a small digital computer. In ten patients, the results were compared with left ventricular angiography. There was a significant correlation between the results of the two methods, r = 0.87, but the radionuclide method tended to produce rather higher figures compared with the angiographic method. Mean inter- and intra-observer differences amounted to 4.2 and 5.2%, respectively. Identification of the plane of the mitral and aortic valves, while outlining the left ventricle, was the least satisfactory part of the procedure.