HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH RSS TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mincey, E. K. Articles by McIntosh, H. W. Search for Related Content PubMed PubMed Citation Articles by Mincey, E. K. Articles by McIntosh, H. W.

A New Parameter of Thyroid Function— The effective Thyroxine Ratio

University of British Columbia, Vancouver General Hospital, Vancouver, Canada
Mallinckrodt Chemical Works, St. Louis, Missouri

Correspondence: For reprints contact: Stephen C. Thorson, Dept. of Medicine, Vancouver General Hospital, Vancouver 9, B.C., Canada.

ABSTRACT

Estimation of serum T₄ concentration in test serum was determined in the presence of test serum itself and expressed as a fraction (effective thyroxine ratio, ETR) of serum T₄ concentration similarly determined in normal serum. Studies of serum from hyperthyroid and hypothyroid patients and euthyroid patients with and without abnormalities of serum T₄-binding proteins indicate a high order of specificity of the ETR in defining abnormal thyroid status irrespective of serum binding protein abnormality.