HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nelson, B. Articles by Andrews, G. A. Search for Related Content PubMed PubMed Citation Articles by Nelson, B. Articles by Andrews, G. A.

Distribution of Gallium in Human Tissues after Intravenous Administration

Medical Division, Oak Ridge Associated Universities, Oak Ridge, Tennessee

Correspondence: For reprints contact: Bill Nelson, Medical Division, Oak Ridge Associated Universities, P.O. Box 117, Oak Ridge, Tenn. 37830.

ABSTRACT

To provide data for radiation dosimetry of ⁶⁷Ga, recently introduced for scanning tumors, we have tabulated the tissue distribution of 23 autopsies after intravenous administration. Relatively high concentrations were usual in the spleen, renal cortex, adrenal, and marrow but assays showed a wide range of values in all tissues. We have also illustrated with autoradiograms an uneven distribution in certain tissues. The radiation dose to those tissues is influenced by cellular localization because much of the energy from ⁶⁷Ga decay is expended by electrons with a very short range.

This article has been cited by other articles:

				T. H. Farncombe, H. C. Gifford, M. V. Narayanan, P. H. Pretorius, E. C. Frey, and M. A. King Assessment of Scatter Compensation Strategies for 67Ga SPECT Using Numerical Observers and Human LROC Studies J. Nucl. Med., May 1, 2004; 45(5): 802 - 812. [Abstract] [Full Text] [PDF]

				L. R. Bernstein Mechanisms of Therapeutic Activity for Gallium Pharmacol. Rev., December 1, 1998; 50(4): 665 - 682. [Abstract] [Full Text] [PDF]