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⁶⁷Ga for Tumor Scanning

Universities of Amsterdam, Berlin, Giessen, and Munich

Correspondence: For reprints contact: Dr. med. Heinz Langhammer, Klinikum Rechts der Isar der Technischen Universität München, 8000 München 80, Ismaninger Strasse 22, Germany.

ABSTRACT

Gallium-67-citrate was administered to 246 patients. The highest percent of positives was found in patients with bronchial carcinoma, thyroid carcinoma, gastric carcinoma, malignant melanoma, and metastases of unknown primary tumors as well as in Hodgkin's disease. The series of patients analyzed according to histological classifications showed no dependence of ⁶⁷Ga accumulation on the morphological type of tumor.

Without the use of laxative and enemas the demonstration of ⁶⁷Ga accumulation in abdominal tumors is complicated by the physiological accumulation in the intestines.

The study of the ⁶⁷Ga accumulation in untreated and treated patients was not conclusive.

In 39 patients with nonmalignant disease ⁶⁷Ga accumulation in the lesion was found in 11, comprising four patients with recent sarcoidosis and one patient with primary tuberculosis. According to biological investigations and measurements of the whole-body retention, the total-body dose normally amounts to 250 mrad/mCi ⁶⁷Ga.