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Brain Scanning in the Diagnosis of Astrocytomas of the Brain

The Johns Hopkins Medical Institutions, Baltimore, Maryland

Correspondence: For reprints contact: Frank H. DeLand, Dept. of Radiology, University of Florida, Gainesville, Florida 32601.

ABSTRACT

The clinical and diagnostic characteristics of 80 patients with astrocytomas of the brain were evaluated. The neurological findings suggested the possibility of a brain tumor in every case. Seizures and papilledema were more commonly associated with the low-grade astrocytomas; motor weakness and mental deterioration with the high-grade tumors. The incidence of papilledema was appreciably less than has been previously reported.

The accuracy of brain scanning and arteriography were similar for the detection of astrocytomas; both were relatively poor for low-grade tumors and acceptable for high-grade. The correct diagnosis was established in 99% of the cases when air contrast studies were done in addition to scanning and arteriography.

The histologic variations in these tumors (other than dedifferentiation) did not appear to correlate with the ability of the tumor to concentrate radionuclides.

FOOTNOTES

^* Present address: See above.