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Analytical Approach to Dynamic Radioisotope Recording

Case Western Reserve University, Department of Medicine, Cleveland, Ohio

Correspondence: For reprints contact: W. J. MacIntyre, University Hospitals of Cleveland, Hanna Pavilion, University Circle, Cleveland, Ohio 44106.

ABSTRACT

To extend the clinical interpretability of externally monitored dynamic isotope data, an analytical approach using either an analog computer or digital computer has been accomplished. The present approach was based on the assumption that dynamic isotope data can be considered to be a series of input-output relationships in terms of the system concept which reduces the problem to simple consecutive steps either of parametric manipulation by analog computer or of graphical analysis by digital computer. An application of this analysis to the radiocardiogram (RCG) has been performed, resulting in clinically useful information concerning the fractional blood volume within right or left heart chamber and pulmonary blood volume in patients with or without congestive heart failure.

FOOTNOTES

^* Present address: Kyoto University Hospital, Central Isotope Div., Sakyo-ku, Kyoto, Japan.