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Measurement of Cardiac Shunting with Technetium-Labeled Albumin Aggregates

Memorial Hospital Medical Center of Long Beach and Earl & Loraine Miller Children's Medical Center, Long Beach, California

Correspondence: For reprints contact: Gary F. Gates, Radiology Dept., Memorial Hospital Center of Long Beach, 2801 Atlantic Ave., Long Beach, Calif. 90801.

ABSTRACT

Right-to-left cardiac shunting was detected and quantitated in three children with tetralogy of Fallot after intravenous injection of ^99mTc-tagged MAA. The test is performed rapidly, and the patient does not require heavy sedation. The method is calculated to have at least a 6,000-fold factor of safety. The only precaution required is that a particle size measurement of each MAA suspension be made before injection. We are impressed with the preliminary results and believe the procedure deserves further investigation.

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