HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Bruno, F. P. Articles by Williams, C. M. Search for Related Content PubMed PubMed Citation Articles by Bruno, F. P. Articles by Williams, C. M.

^99mTc-Iron Hydroxide Aggregates for Lung Scanning

University of Florida College of Medicine and Veterans Administration Hospital, Gainesville, Florida

Correspondence: For reprints contact: Clyde M. Williams, Dept. of Radiology, University of Florida-Gainesville, Teaching Hospital and Clinics, Gainesville, Fla. 32601.

ABSTRACT

A simple method for incorporating ^99mTc into iron hydroxide particles using sterile, pyrogen-free reagents has been described. The compound consists of particles with a size distribution of 3–30 microns. Internal distribution studies using rabbits show that about 84% of the intravenously injected radioactivity is trapped by the lung, the remainder being deposited mainly in liver (7%) and carcass (7%). Clinical studies have resulted in excellent lung scans. Hazards from radiation and iron toxicity are considered to be negligible.