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Estimation of Residual Urine and Urine Flow Rates Without Urethral Catheterization

Albert Einstein College of Medicine, Bronx, New York

Correspondence: For reprints contact: M. Donald Blaufox, Dept. of Medicine—Radiology, Albert Einstein College of Medicine of Yeshiva University, 1300 Morris Park Ave., Bronx, N.Y. 10461.

ABSTRACT

Thirty patients (20 with obstructive uropathy and 10 normal) have been studied to evaluate the use of radionuclides for the estimation of residual urine and urine flow rates without urethral catheterization. The residual urine was estimated from the radioactivity detected in the bladder area 45 min or longer after the intravenous injection of ¹³¹I-orthoiodohippurate. The mean residual volume determined in 20 patients with obstructive uropathy by the isotopic method was 77 ± 17 ml (s.e.). Catheterization performed immediately after the isotope study revealed a residual of 80 ± 18 ml (s.e.). This difference is not significant (0.3 < p < 0.4). None of the 10 normal subjects had a significant residual by the isotopic method; they were not catheterized. The mean urine flow rate in the normal subjects was 16.1 ml/sec ± 8.3 (s.d.) and 5.9 ml/sec ± 3.3 (s.d.) in the abnormal patients (p < 0.01). The method described is accurate and reliable and should be used in preference to urethral catheterization to determine residual urine volume and urine flow rates in patients with lower urinary tract obstruction.

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