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The Journal of Nuclear Medicine Vol. 11 No. 1 12-14
© 1970 by Society of Nuclear Medicine
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Estimation of Spleen Size in Sickle Cell Anemia

L. D. Samuels and C. Stewart

Children's Hospital, Columbus, Ohio

Correspondence: For reprints contact: L. D. Samuels, Children's Hospital, Columbus, Ohio 43205.

ABSTRACT

Technetium-99m-sulfur colloid liver-spleen scans have been performed in a series of 11 children with sickle cell anemia and compared with series of children with clinically normal spleens and with palpable splenomegaly. Spleens of children with sickle cell disease are significantly smaller and half the time were not visualized at all. The implications of atrophy S versus nonfunctioning of the splenic tissue are discussed.






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Copyright © 1970 by the Society of Nuclear Medicine.