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Dynamic Clinical Studies with Radioisotopes and the Scintillation Camera: IV. ^99mTc-Sodium Pertechnetate Cardiac Blood-Flow Studies

Michael Reese Hospital and Medical Center, Chicago, Illinois

Correspondence: For reprints contact: G. Burke, Radioisotope Laboratory, Michael Reese Hospital and Medical Center, 29th St. and Ellis Ave., Chicago, Ill. 60616.

ABSTRACT

The scintillation camera has been used for dynamic studies of cardiopulmonary blood flow with ^99mTc-sodium pertechnetate. Visualization of the cardiac chambers achieved with this method compares favorably with that obtained on conventional angiocardiography. The technique has been found of value in determining relative cardiac chamber size, detection of intracardiac shunts and demonstration of pericardial effusions as well as in the diagnosis of superior vena caval syndrome.

Determinations of central mean transit time and its arterial and venous subdivisions from inspection of the scintiphoto sequence yield data entirely analogous to those obtained by the more tedious mathematical analysis of dual-probe radiopulmonary cardiogram curves in normal subjects and patients with cardiac disease. Cardiac blood-flow study with the scintillation camera is without hazard to the patient and is of significant diagnostic value in a variety of cardiac disorders.