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^99mTc-Ferric Hydroxide Macroaggregates for Pulmonary Scintiphotography

Donner Laboratory of Biophysics and Medical Physics and Lawrence Radiation Laboratory, Berkeley, California

Correspondence: For reprints contact: Yukio Yano, Donner Laboratory, University of California, Berkeley, Calif. 94720.

ABSTRACT

The physical advantages of ^99mTc can be used for lung scanning with this new compound, ^99mTc-Fe(OH)₃-MA, which is easily and rapidly prepared. There is about 85% uptake of ^99mTc in the lungs with insignificant uptake in other organs. The high photon yield and low radiation dose permits lung scans to be performed in a few minutes and dynamic blood-flow studies are possible with the scintillation camera using 2–3-sec exposures.