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Rare Earth Nuclides as Potential Agents for Skeletal Imaging

Upstate Medical Center, State University of New York, Syracuse, New York

Correspondence: For reprints contact: R. E. O'Mara, College of Medicine, Dept. of Radiology, State University of New York, Upstate Medical Center, 750 E. Adams St., Syracuse, N.Y. 13210.

ABSTRACT

Good skeletal images can be obtained on the Anger camera using certain radionuclides of the heavier lanthanons as chelates of HEDTA. With rectilinear scanning, slow scanning speeds and long collimators with thick septa necessary for high-energy gamma emissions need not be used. These nuclides are readily and cheaply produced in a nuclear reactor without significant radioactive impurities.

Of the rare-earth nuclides evaluated, ¹⁵³Sm and ¹⁷¹Er have physical characteristics best suited for imaging in man. ¹⁵³Sm has the advantage of greater convenience because its half-life is 47 hr and it has higher efficiency with the Anger camera. ¹⁷¹Er has the advantage of a lower estimated radiation dose and a higher ratio of external photons per disintegration.