FIGURE 5.  H₂¹⁵O PET. Tumor perfusion (K₁, k₂, DV, and VB values) measured in WT-MH3924A (n = 7) and hANG-MH3924A (n = 8) of ACI rats; 2D acquisition (1-tissue compartment model). hANG-expressing tumors showed a significantly increased K₁ (A), whereas k₂ remained unchanged (B). The fractional volume of distribution (DV) increased significantly in hANG-MH3924A (C), whereas the vascular fraction (VB) showed no difference (D).