FIGURE 1.  Subject 3, with histologically proven malignancy in left prostate lobe. (A) Coronal whole-body ¹⁸F-fluorocholine PET image 7 min after injection shows focal uptake in left lobe of prostate (large arrow) corresponding to malignant lesion on biopsy. Increasing bladder activity is evident in second FOV of this image (small arrow). (B) Coronal image of pelvis 1 h after injection shows increasing activity in prostate lesion. Images are shown at same intensity. (C) Graph depicts distribution of SUVmax increase in transverse slice of prostate at midsection (inset: delayed transverse image). SUVmax in lesion increased by 22% (+4.4), whereas SUVmax in contralateral benign area decreased by 6% (–0.4).