FIGURE 6.  PET-based infarct sizing using automated delineation. Depicted are linear regression (A) and Bland–Altman analysis (B) of infarct size defined as the proportion of MCA_3D of infarcted myocardium as derived by PET and automated segmentation with standard parameters (50% threshold, postoperative (post-OP) scan only, MCA_3D) in comparison with histomorphometry. Additionally, nonstandard PET analysis with inclusion of both pre- and post-OP scans for calculation of infarct size (C and D) and nonstandard PET analysis using MCA_slices instead of MCA_3D (E and F) were compared with PET analysis with standard parameters (50% threshold, postoperative scan only, MCA_3D). In both cases, linear regression (C and E) and Bland–Altman analyses (D and F) are shown. Solid line in Bland–Altman plots depicts mean difference; dashed lines depict limits of agreement (mean ± 2 SD).