FIGURE 6.  Plots of unmetabolized ¹¹C-DASB vs. time for same subjects on baseline scan days (A) and occupancy scan days (B). Subjects had plasma sertraline level 13 ng/mL on day of occupancy study. On baseline days, most subjects had lower unmetabolized ¹¹C-DASB at 2 min than at 12 min. After subjects received saturating doses of sertraline, pattern was reversed. Subjects are identified with unique markers.