FIGURE 6.  Box-plot comparison of whole-brain PSR values obtained for men and women. Middle 50% of data lie within box, with ends of vertical lines representing maximum and minimum data values. Points outside minimum and maximum values are considered outliers. (A) PSR values calculated on basis of leucine kinetics without correction for plasma total sum of LNAAs. (B) PSR values after normalization of plasma total sum of LNAAs to standard value of 1,000 µmol/L (PSR'). Although neither measure of PSR is significantly different between the sexes, correction for plasma total sum of all LNAAs results in smaller difference between mean male and female PSRs, indicating a small effect of total plasma LNAA levels on PSR measure.