FIGURE 3.  Example of patient with large, cranial meningioma. Patient already had undergone surgery 4 times and had had external beam radiotherapy before ¹⁷⁷Lu-octreotate. (A) MR image 1 wk after first cycle of ¹⁷⁷Lu-octreotate shows meningioma (arrow, curved arrow) with some extracranial involvement. (B) MR image 1 mo after final dose of ¹⁷⁷Lu-octreotate. Intracranial part of meningioma has increased (arrows). Extracranial, exophytic parts have increased as well (arrowheads). (C) Photograph of patient 18 mo after last dose of ¹⁷⁷Lu-octreotate (view from right, posterooblique). Patient had undergone surgery and had had external beam radiotherapy again and had just finished 6 cycles of cisplatin without therapeutic effect. Arrow indicates very large, extracranial part of meningioma with ulcerated skin.