FIGURE 2. A 52-y-old man with colon cancer, after surgery, increasing carcinoembryonic antigen (CEA) serum levels, and a repeated negative CT study. (A) PET shows focal area of abnormal ¹⁸F-FDG uptake in left upper abdomen, suggestive of recurrence. (B) Hybrid PET/CT images precisely localized this uptake anterior to tail of pancreas, medial to spleen. Retrospective evaluation of CT performed 2 mo earlier and examination of CT study performed simultaneously with PET did not reveal any abnormalities. Surgeons used location provided by PET/CT for reexploration of abdomen and recurrent tumor in colon was found.