Click on image to view larger version.



FIGURE 7. Blockade of CD4+ cell migration to colon after anti-{alpha}4 antibody injection. Ex vivo planar scintigraphic images of isolated cleaned colon show distinct colon radioactivity uptake in mouse with TNBS colitis transferred with sensitized 111In-labeled CD4+ lymphocytes (A). Colon radioactivity uptake is decreased after treatment with anti-{alpha}4 antibody (B). Images are representative of 5 mice per group.