FIGURE 2. ^99mTc-IL2 scintigraphy (A) of a patient with a small melanoma near the right clavicle (B). Despite the small size of the tumor (green arrow), regional lymph nodes are also detectable (red arrow), reflecting active immune response inside primary and metastatic tumors. T/B ratio was 1.44. (C) CD25 staining showed a mild positivity for neoplastic cells and a strong diffuse positivity for lymphocytes.