FIGURE 2. Tumor versus kidney uptake. Radiolabeled DOTA-
-MSH analogs (
, 111In-DOTA-MSHoct;
, 111In-DOTA-NAPamide;
, 67Ga-DOTA-NAPamide) were injected into melanoma-bearing mice and radioactivity accumulated in tumor and kidney was measured 4, 24, and 48 h after injection. Results are expressed as tumor AUC (left), kidney AUC (middle), and tumor-to-kidney ratios of AUC (right) (n = 8).