FIGURE 1. Anterior (left) and posterior (right) whole-body scintigraphy of patient 1. (A) Correlating bone scintigraphy shows multiple sites of pathologic uptake (arrow). (B) Baseline Z-¹²³I-MIVE scintigraphy shows multiple sites of pathologic uptake (arrow) in axial skeleton, skull, and left pleura. (C) Z-¹²³I-MIVE scintigraphy 4 wk after starting tamoxifen shows complete blocking of pathologic uptake in lesions visible on baseline scintigraphy. Thyroid uptake (C) is due to suboptimal blocking of free ¹²³I uptake. Masking of intestinal and hepatic activity was done by computer processing after acquisition.