FIGURE 1. (A) ⁷⁶Br-Bromide time–activity curve in patient 2 with glioblastoma multiforme shows radioactivity of plasma, normal brain tissue, and tumor. Dotted and solid lines through tissue data points represent fits by 2- and 3-compartment models, respectively. (B) Logan plot of same time–activity curve as in A. (C) Patlak plot of same time–activity curve as in A, using linear regression from 60 min to end of scan. There is no significant difference between Patlak time (exposure time) and real PET time in case of ⁷⁶Br-bromide PET.