FIGURE 3. Example of the performed analysis. (A) CT image with thresholds [-160 HU, 240 HU] showing regions that define oral CT contrast, tumor, and reference tissue. (B) CT image after replacement of contrast-enhanced pixels by normal values. (C) PET emission image attenuation corrected with CT image A. (D) PET emission image attenuation corrected with CT image B, resulting in approximation of true 18F-FDG uptake. (E) Difference image C - D normalized to D, showing percentage error due to attenuation correction with CT contrast-enhanced pixels. Maximal difference is 9.6%.