FIGURE 1. An 86-y-old woman (patient 1) with IgG multiple myeloma developed carpal tunnel syndrome, progressive submandibular masses, and swelling of tongue. At time of scintigraphy, patient did not have abdominal symptoms but later developed severe constipation due to intestinal amyloidosis. ^99mTc-Aprotinin scintigrams show pathologic uptake in heart and parts of intestine (A, abdominal anterior projection), both hands (B, dorsal view), and tongue and submandibular glands (C, left lateral projection of head).