FIGURE 3. Time-activity curves generated from direct arterial sampling after arterial administration of 37 MBq of ⁶⁴Cu-ATSM to generate input function (n = 3 dogs). (A) Plot shows percentage of octanol-extractable ⁶⁴Cu-ATSM with respect to total ⁶⁴Cu-ATSM blood activity as function of time. (B) Plot shows total amount of radioactivity in arterial blood after injection of ⁶⁴Cu-ATSM as function of time and amount of radioactivity in form of ⁶⁴Cu-ATSM.