FIGURE 1. A 70-y-old woman (patient 1) with right hemiparesis and aphasia. (A) CT image obtained 1.5 h after onset shows no definite abnormal density. (B and C) SPECT images with HMPAO obtained 3 h after onset show area of hyperactivity in left temporal cortex with surrounding cortical hypoactivity. L/C of area of hyperactivity is 2.95 and that of area of hypoactivity is 0.33. (D) Angiogram (lateral view) of left internal carotid artery (ICA) obtained 3.5 h after onset (before treatment) shows middle cerebral artery (MCA) occlusion but spontaneous recanalization (i.e., capillary blush and early venous filling) in temporal region. (E) Angiogram (lateral view) of left ICA obtained 4.5 h after onset (after intraarterial thrombolysis) shows partial recanalization of left MCA. (F) CT image obtained 9 h after onset shows hemorrhagic transformation with extensive brain edema in left temporal region.