FIGURE 3. Effects of chemotherapeutic agents on binding of DOTA-LAN and number of binding sites per cell for high- and low-affinity sites (1 and 2), respectively, in BxPC-3 cells (n = 3; mean ± SEM). gemca = gemcitabine (1 and 2 µg/mL); cisPt = cisplatin (2.5 and 5 µg/mL); cpt = camptothecin (1.5 and 3 µg/mL); mito = mitomycin C (0.1 and 0.2 µg/mL); doxo = doxorubicin (1 and 2 µg/mL).