FIGURE 5. Example of high-impact study. This patient was assessed as having stage IIB disease on basis of CT findings and was being considered for radical radiotherapy. In addition to confirming mediastinal nodal disease (vertical arrow), PET showed previously unrecognized metastases on left adrenal (oblique arrow) and dome of right hepatic lobe (horizontal arrow). Accordingly, patient received only palliative radiotherapy. Follow-up confirmed progressive systemic metastasis within 6 mo.