FIGURE 3. (A–C) Three noise realizations for simulated WB images. Image total counts are 10⁴, 10⁵, and 10⁶ for A, B, and C, respectively, corresponding to SNRs of approximately 1, 4, and 12, respectively. (D) Patient image. In this patient, uptake in heart was higher than that used in simulation, and kidney uptake was lower. Source distribution was estimated from several patient images, and, as illustrated, individual variations occur.