FIGURE 2. Histogram comparing effects of anatomic standardization. Horizontal axis represents SD for each individual pixel for T1-weighted summed MR images across 6 monkeys. Vertical axis represents percentage of brain volume, calculated as number of pixels in each range divided by total number of pixels in brain. Curves illustrate stereotactic realignment alone with no linear scaling (NS), with linear scaling (LS), and with linear scaling and nonlinear warping (LS+NW).