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Figure 6


FIGURE 6. Effect of eniluracil (EU) on 18F time–activity curves in tissues, organs, and arterial plasma after intravenous injection of [18F]FU (FU). Tissue and organ time–activity curves (A–C; n = 4 and 2 for FU + EU and FU-only, respectively) were extracted from PET images, whereas plasma curves (D; n = 5 and 2 for FU + EU and FU-only, respectively) were obtained by direct arterial sampling. Tissue and organ data were normalized at the final time point to values obtained by ex vivo assay of excised tissue samples obtained after killing at 2 h. Data are expressed in terms of SUV. Note that ordinate scales differ in (A–D).