FIGURE 2. A 32-y-old woman with stage 3 giant cell tumor of tibial head. (A) Radiograph shows radiolucent, ill-defined lesion located eccentrically in epiphysis and adjacent metaphyseal region with destruction of dorsomedial cortex. (B) MR image shows homogeneous uptake of gadolinium–diethylenetriaminepentaacetic acid within lesion and tumoral infiltration of popliteus muscle. (C) PET image shows highly hypermetabolic lesion suggestive of malignant tumor (T/B, 35.0). (D) Gross specimen shows subchondral extension, cortical destruction, and typical hemorrhagic aspect of giant cell tumor.